The Mighty Mitochondria What are mitochondria and why are they so important to our understanding of many neurological diseases? In this course, we will explore what mitochondria are and their role in different cells and specifically in the cells of the brain. Mitochondria are thought to be the cell’s powerhouse, but they are not found in all cells. Furthermore, their dysregulation, either through genetic mutations or environmental factors, leads to profound consequences for human health. Topics to be covered are the structure and function of mitochondria, cell death, oxidative stress, aging, neurological diseases, and rare genetic diseases. (BIOL 0145; not open to first-year students; open to neuroscience majors and biology majors; others by waiver). 3hrs lecture.

Fundamentals of Cellular and Molecular Neuroscience Neurons are the building blocks of complex circuits that underlie perception and behavior. In this course we will examine the molecular and cellular basis of neuron structure and function. The topics include the molecular and cellular basis of action potential propagation, the molecular biology of synaptic transmission, the molecular mechanisms of synaptic plasticity, and the molecular mechanisms of sensory transduction. Laboratory exercises will train students in commonly used neurobiology techniques and engage students in novel investigations. (BIOL 0145 (Note: AP credit in biology cannot be used to satisfy this requirement) Open to neuroscience majors, nonmajors by waiver; Not open to seniors).

Neural Coding: Visualizing How the Brain Computes How does the brain go from an electrical signal to recognizing friends? In this course we will learn to use MATLAB to explore visually how the brain uses electrical signals to compute information. By using MATLAB as the frame for the class, students will gain skills in using a fundamental tool in neuroscience. In addition, through the use of introductory lectures, readings, in class programming activities, and discussion, students will deepen their understanding of how sensory information is encoded and then decoded. No experience using MATLAB necessary.   (NSCI 0251 and NSCI 252; Open to junior and senior neuroscience majors by instructor approval). Due to restricted capacity, neuroscience seniors needing a senior seminar in order to fulfill their senior work requirement will be given priority.

Molecular Neurogenetics: A Techniques Lab How do we study the molecular properties of neurons in the laboratory? Have you ever wondered what it is like to work in a molecular neuroscience lab? In this course, we take a deep dive into the techniques widely used to molecularly identify neurons, such as immunostaining and single-cell sequencing. We will learn how to genotype animals and then explore methods in protein expression analysis. In this class, we will also explore how bioinformatics is shaping our current understanding of the brain and the cells within it. Utilizing the consecutive course periods of the winter term, students will have the unique opportunity to design, perform, and analyze experiments featuring modern cellular and molecular neuroscience techniques.

Methods in Systems Neuroscience Our brains are series of connected neurons forming circuits. The properties of these neurons and circuits dictate their role in our behavior. This interaction is the foundation of systems neuroscience.  In this course students will deepen their understanding of the fundamental properties of these neural circuits. Students will gain knowledge of the current methods of studying these circuits, including their promise for future research directions as well as their flaws. We will focus on learning the principles of neural circuitry and discussing primary literature.  (NSCI 0251 and NSCI 0252; open to junior and senior neuroscience majors; others by waiver).

Amanda Crocker

Reviews and ratings for Amanda Crocker at Middlebury College.Amanda Crocker teaches Mighty-chondria, Cellular/MolecularNeuroscience, Neural Coding and more.  Explore top rated instructors and find the best for you.Is Amanda Crocker good ? Find out on MiddCourses.

The lectures covered a lot of content in little time. The homework was super light aside from the single lab report and two projects. The homework consisted of one weekly worksheet that was easy to complete given you understood the content. The labs were boring.

I really enjoyed this course and found the material fascinating. The course often moved quickly and information could be disorganized. However, much of the material built upon itself and was therefore reviewed, making it easier to absorb. Prof Crocker was also extremely accommodating and always answered all questions in depth. She is clearly very knowledgeable and passionate about the subject!

This class was amazing. Professor Crocker takes a project based approach and makes sure we are able to relay the material in a concise manner. We also had a mock grant project at the end of the year which forced us to look into scientific literature, but with her help you actually get a lot out of it and learn a lot. Highly recommend this class.